SCHEMBL2007656

SCHEMBL2007656

[c]1c[nH]c2nnccc12

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL82645 0.65
SCHEMBL2007628 0.65
SCHEMBL452564 0.61
SCHEMBL1996526 0.58
Hydrochloric Acid SCHEMBL30870484 0.56 MAPK1 (0.35)
SCHEMBL2009078 0.56
SCHEMBL3664422 0.56
SCHEMBL30751016 0.55 ATM (0.38)
SCHEMBL19250472 0.55 GSK3B (0.39)
SCHEMBL2561531 0.55

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2897618-B1 CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS NEUPHARMA INC (US) 2021-11-17 EP claimed
US-10457641-B2 Certain chemical entities, compositions, and methods NEUPHARMA, INC. (US) 2019-10-29 US claimed
US-20170334859-A1 CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS NEUPHARMA, INC. 2017-11-23 US claimed
US-9688635-B2 Certain chemical entities, compositions, and methods NEUPHARMA, INC. (US) 2017-06-27 US claimed
US-20150246885-A1 CERTAIN CHEMICAL ENTITES, COMPOSITIONS, AND METHODS NEUPHARMA, INC. 2015-09-03 US claimed
EP-2897618-A1 CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS Neupharma, Inc. (US) 2015-07-29 EP claimed
WO-2014047648-A1 CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS NEUPHARMA, INC. (US) 2014-03-27 WO claimed
US-20100190777-A1 COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR PLEXXIKON INC. (US) 2010-07-29 US claimed
EP-2170830-A1 COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR PLEXXIKON, INC. (US) 2010-04-07 EP claimed
WO-2009012283-A1 COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR PLEXXIKON INC. (US) 2009-01-22 WO claimed
US-20210353602-A1 COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR PLEXXIKON INC (US) 2021-11-18 US disclosed
EP-2897618-B1 CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS NEUPHARMA INC (US) 2021-11-17 EP disclosed
US-20210346358-A1 COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR PLEXXIKON INC (US) 2021-11-11 US disclosed
CN-104812389-B Certain chemical entities, compositions, and methods 润新生物公司 2020-07-17 CN disclosed
US-10457641-B2 Certain chemical entities, compositions, and methods NEUPHARMA, INC. (US) 2019-10-29 US disclosed
WO-2008103866-A1 SYNTHESIS OF INDOLES MICROBIA, INC. (US) 2008-08-28 WO disclosed
EP-1931632-A2 USEFUL INDOLE COMPOUNDS Microbia Inc. (US) 2008-06-18 EP disclosed
WO-2008019357-A2 INDOLE COMPOUNDS IRONWOOD PHARMACEUTICALS, INC. (US) 2008-02-14 WO disclosed
US-20070203209-A1 Useful indole compounds IRONWOOD PHARMACEUTICALS, INC. 2007-08-30 US disclosed
WO-2007022501-A2 USEFUL INDOLE COMPOUNDS MICROBIA, INC. (US) 2007-02-22 WO disclosed