Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 5/20 | 0.60 |
| ▸ | AR | P10275 | 2/20 | 0.51 |
| ▸ | HTR6 | P50406 | 2/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.49 |
| ▸ | GRM5 | P41594 | 1/20 | 0.46 |
| ▸ | PLK1 | P53350 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.45 |
| ▸ | CSF1R | P07333 | 1/20 | 0.45 |
| ▸ | KIT | P10721 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31568445 | 0.86 | MRGPRX4 (0.76) | MRGPRX4HTR6SLC6A4GRM5MAOB | |
| SCHEMBL22469778 | 0.86 | MRGPRX4 (0.76) | MRGPRX4HTR6SLC6A4GRM5MAOB | |
| SCHEMBL13929791 | 0.84 | MAOB (0.59) | MRGPRX4MAOBHTR1AADRA1DADRA1A | |
| SCHEMBL3490042 | 0.80 | MAOB (0.57) | MRGPRX4ARMAOBHTR1AADRA1D | |
| SCHEMBL13232461 | 0.80 | GRM5 (0.62) | MRGPRX4HTR6GRM5MAOB | |
| SCHEMBL171847 | 0.79 | NPC1 (0.58) | HTR1AADRA1DADRA1AADRA1BHPGD | |
| SCHEMBL23235862 | 0.79 | AR (0.55) | MRGPRX4ARSLC6A4CSF1RNPC1 | |
| SCHEMBL12864874 | 0.79 | MAOB (0.56) | MRGPRX4MAOBHTR1AADRA1DADRA1A | |
| SCHEMBL12112551 | 0.78 | SMN1; SMN2 (0.56) | MRGPRX4SLC6A4PLK1HPGDNPC1 | |
| SCHEMBL4204671 | 0.78 | MRGPRX4 (0.67) | MRGPRX4ARHTR6SLC6A4GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018071348-A1 | QUINOXALINE COMPOUNDS AS TYPE III RECEPTOR TYROSINE KINASE INHIBITORS | DEVELOPMENT CENTER FOR BIOTECHNOLOGY (TW) | 2018-04-19 | — | — | WO | disclosed |