Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | CPT2 | P23786 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20078060 | 0.84 | TDP1 (0.38) | FFAR1CPT2TDP1 | |
| SCHEMBL17036862 | 0.81 | CYP2C19 (0.41) | CYP2C19FFAR1CPT2TDP1POLB | |
| SCHEMBL8195036 | 0.79 | CYP2C19 (0.40) | CYP2C19FFAR1CPT2TDP1POLB | |
| SCHEMBL15403688 | 0.78 | CYP2C19 (0.36) | CYP2C19POLBBLMATMHDAC3 | |
| SCHEMBL15403801 | 0.78 | CYP2C19 (0.39) | CYP2C19FFAR1CPT2TDP1POLB | |
| SCHEMBL20673332 | 0.78 | CYP2C19 (0.39) | CYP2C19FFAR1CPT2TDP1POLB | |
| SCHEMBL27822244 | 0.78 | CYP2C19 (0.55) | CYP2C19TDP1POLBBLMATM | |
| SCHEMBL15402225 | 0.76 | HDAC3 (0.38) | CYP2C19FFAR1CPT2TDP1POLB | |
| SCHEMBL9995801 | 0.75 | CYP2C19 (0.40) | CYP2C19POLBBLMATMHDAC3 | |
| SCHEMBL6871500 | 0.75 | CYP2C19 (0.52) | CYP2C19TDP1POLBBLMATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9950001-B2 | Polynucleotides having bioreversible groups | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-04-24 | — | — | US | disclosed |