Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.32 |
| ▸ | BTN3A1 | O00481 | 3/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23813342 | 0.91 | CYP3A4 (0.36) | CYP3A4CYP2C9BTN3A1RIPK1 | |
| SCHEMBL17712262 | 0.91 | TMPRSS2 (0.40) | CYP3A4CYP2C9TMPRSS2BTN3A1RIPK1 | |
| SCHEMBL17712260 | 0.91 | TMPRSS2 (0.40) | CYP3A4CYP2C9TMPRSS2BTN3A1RIPK1 | |
| SCHEMBL24462486 | 0.91 | TMPRSS2 (0.40) | CYP3A4CYP2C9TMPRSS2BTN3A1RIPK1 | |
| SCHEMBL17712257 | 0.89 | TMPRSS2 (0.40) | CYP3A4CYP2C9TMPRSS2BTN3A1RIPK1 | |
| SCHEMBL18309987 | 0.89 | TMPRSS2 (0.40) | CYP3A4CYP2C9TMPRSS2BTN3A1RIPK1 | |
| SCHEMBL17712519 | 0.89 | TMPRSS2 (0.40) | CYP3A4CYP2C9TMPRSS2BTN3A1RIPK1 | |
| SCHEMBL17712512 | 0.89 | TMPRSS2 (0.39) | CYP3A4CYP2C9TMPRSS2BTN3A1RIPK1 | |
| SCHEMBL24976214 | 0.89 | TMPRSS2 (0.39) | CYP3A4CYP2C9TMPRSS2BTN3A1RIPK1 | |
| SCHEMBL17712316 | 0.89 | TMPRSS2 (0.39) | CYP3A4CYP2C9TMPRSS2BTN3A1RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9949994-B2 | Methods for treating Filoviridae virus infections | GILEAD SCIENCES, INC. (US) | 2018-04-24 | — | — | US | disclosed |