Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 1/20 | 0.45 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.34 |
| ▸ | AXL | P30530 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20079172 | 1.00 | KAT2B (0.45) | KAT2BKDM2BAXLBTKCHRM1 | |
| SCHEMBL14883730 | 0.82 | POLB (0.41) | CHRM1 | |
| SCHEMBL21386122 | 0.82 | KAT2B (0.47) | KAT2BKDM2B | |
| SCHEMBL21386121 | 0.82 | KAT2B (0.47) | KAT2BKDM2B | |
| SCHEMBL2621563 | 0.80 | KAT2B (0.32) | KAT2BAXL | |
| SCHEMBL23554427 | 0.79 | KAT2B (0.39) | KAT2BKDM2B | |
| SCHEMBL19807290 | 0.79 | KAT2B (0.39) | KAT2BKDM2B | |
| SCHEMBL18099727 | 0.79 | KAT2B (0.39) | KAT2BKDM2B | |
| SCHEMBL18236741 | 0.78 | KAT2B (0.47) | KAT2BKDM2BCHRM1 | |
| SCHEMBL18236730 | 0.78 | KAT2B (0.47) | KAT2BKDM2BCHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9951065-B2 | Benzimidazole and imadazopyridine carboximidamide compounds | GILEAD SCIENCES, INC. (US) | 2018-04-24 | — | — | US | disclosed |