Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 19/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 18/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.38 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.31 |
| ▸ | HTR3B | O95264 | 1/20 | 0.31 |
| ▸ | HTR3A | P46098 | 1/20 | 0.31 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.31 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25530516 | 1.00 | SLC6A4 (0.41) | SLC6A4SLC6A3SLC6A2HTR3EHTR3B | |
| SCHEMBL817636 | 0.78 | SLC6A4 (0.30) | SLC6A4 | |
| SCHEMBL5703325 | 0.76 | — | — | |
| SCHEMBL5703284 | 0.76 | — | — | |
| SCHEMBL5703328 | 0.76 | — | — | |
| SCHEMBL4351529 | 0.74 | USP2 (0.32) | — | |
| SCHEMBL8280715 | 0.74 | USP2 (0.32) | — | |
| SCHEMBL25532376 | 0.74 | USP2 (0.32) | — | |
| SCHEMBL419801 | 0.74 | DPP4 (0.34) | — | |
| SCHEMBL420711 | 0.74 | DPP4 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9951065-B2 | Benzimidazole and imadazopyridine carboximidamide compounds | GILEAD SCIENCES, INC. (US) | 2018-04-24 | — | — | US | disclosed |