Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGFRL1 | Q5TC84 | 18/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 16/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16743564 | 1.00 | OGFRL1 (0.37) | OGFRL1OPRL1OPRK1OPRM1OPRD1 | |
| SCHEMBL15858179 | 1.00 | OGFRL1 (0.37) | OGFRL1OPRL1OPRK1OPRM1OPRD1 | |
| SCHEMBL18086595 | 0.98 | OGFRL1 (0.38) | OGFRL1OPRL1OPRK1OPRM1OPRD1 | |
| SCHEMBL3046521 | 0.98 | OGFRL1 (0.38) | OGFRL1OPRL1OPRK1OPRM1OPRD1 | |
| SCHEMBL17389314 | 0.98 | OGFRL1 (0.38) | OGFRL1OPRL1OPRK1OPRM1OPRD1 | |
| SCHEMBL12436681 | 0.98 | OGFRL1 (0.38) | OGFRL1OPRL1OPRK1OPRM1OPRD1 | |
| SCHEMBL15847181 | 0.98 | OGFRL1 (0.38) | OGFRL1OPRL1OPRK1OPRM1OPRD1 | |
| SCHEMBL16743560 | 0.98 | OGFRL1 (0.38) | OGFRL1OPRL1OPRK1OPRM1OPRD1 | |
| SCHEMBL880919 | 0.94 | OGFRL1 (0.35) | OGFRL1OPRL1OPRK1OPRM1OPRD1 | |
| Acetic Acid SCHEMBL15466895 | 0.88 | OGFRL1 (0.39) | OGFRL1OPRL1OPRK1OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9951038-B2 | Quinazolin-4(3H)-one-type piperidine compounds and uses thereof | PURDUE PHARMA L.P. (US) | 2018-04-24 | — | — | US | disclosed |