SCHEMBL20080469

SCHEMBL20080469

OC(Nc1c(F)cccc1F)c1ccc(-n2nc(C(F)(F)F)cc2C2CC2)nc1

nearest known ligand 0.65

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CRACR2A Q9BSW2 20/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1668009 0.79 CRACR2A (1.00) CRACR2A
SCHEMBL20006293 0.76 CRACR2A (0.81) CRACR2A
SCHEMBL19335830 0.76 CRACR2A (0.68) CRACR2A
SCHEMBL19335861 0.75 CRACR2A (0.68) CRACR2A
SCHEMBL1879487 0.75 CRACR2A (1.00) CRACR2A
SCHEMBL19335860 0.73 CRACR2A (0.58) CRACR2A
SCHEMBL1667933 0.73 CRACR2A (0.81) CRACR2A
SCHEMBL1668206 0.73 CRACR2A (1.00) CRACR2A
SCHEMBL1668067 0.72 CRACR2A (1.00) CRACR2A
SCHEMBL19335888 0.72 CRACR2A (0.60) CRACR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2509955-B1 PYRAZOLE DERIVATIVES AS MODULATORS OF CALCIUM RELEASE-ACTIVATED CALCIUM CHANNEL RHIZEN PHARMACEUTICALS S A (CH) 2018-04-25 EP disclosed