SCHEMBL20080593

SCHEMBL20080593

COc1cc(C2OC3(CCOCC3)c3c4c(nc(C(C)C)c32)C(OC(C)=O)C2(CC2)CC4O)ccc1C(F)(F)F

nearest known ligand 0.80

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CETP P11597 20/20 0.80

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20080590 1.00 CETP (0.80) CETP
SCHEMBL15182804 0.89 CETP (0.64) CETP
SCHEMBL14697726 0.89 CETP (1.00) CETP
SCHEMBL14708781 0.89 CETP (1.00) CETP
SCHEMBL20080597 0.85 CETP (0.78) CETP
SCHEMBL20080595 0.85 CETP (0.78) CETP
SCHEMBL20080556 0.85 CETP (0.91) CETP
SCHEMBL20080604 0.83 CETP (0.70) CETP
SCHEMBL20080572 0.83 CETP (0.88) CETP
SCHEMBL20080497 0.80 CETP (1.00) CETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2760868-B1 FURO[3,4-C]QUINOLINE DERIVATIVES, MEDICAMENTS CONTAINING SUCH COMPOUNDS, THEIR USE AND PROCESS FOR THEIR PREPARATION BOEHRINGER INGELHEIM INT (DE) 2018-04-25 EP disclosed