Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 20/20 | 1.00 |
| ▸ | ATRIP | Q8WXE1 | 20/20 | 1.00 |
| ▸ | GAK | O14976 | 1/20 | 0.80 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.80 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.80 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.80 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.80 |
| ▸ | MTOR | P42345 | 1/20 | 0.80 |
| ▸ | PRKDC | P78527 | 1/20 | 0.80 |
| ▸ | ATM | Q13315 | 1/20 | 0.80 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17501126 | 1.00 | ATR (1.00) | ATRATRIPGAKCYP3A4CYP2C8 | |
| SCHEMBL17501435 | 0.94 | ATR (1.00) | ATRATRIPGAKCYP3A4CYP2C8 | |
| SCHEMBL20081847 | 0.94 | ATR (1.00) | ATRATRIPGAKCYP3A4CYP2C8 | |
| SCHEMBL17501255 | 0.94 | ATR (1.00) | ATRATRIPGAKCYP3A4CYP2C8 | |
| SCHEMBL17501617 | 0.90 | ATR (1.00) | ATRATRIPGAKCYP3A4CYP2C8 | |
| SCHEMBL20081798 | 0.90 | ATR (1.00) | ATRATRIPGAKCYP3A4CYP2C8 | |
| Elimusertib SCHEMBL25080815 | 0.89 | ATR (1.00) | ATRATRIPGAKCYP3A4CYP2C8 | |
| Elimusertib SCHEMBL20081876 | 0.89 | ATR (1.00) | ATRATRIPGAKCYP3A4CYP2C8 | |
| Elimusertib SCHEMBL31602087 | 0.89 | ATR (1.00) | ATRATRIPGAKCYP3A4CYP2C8 | |
| Elimusertib SCHEMBL30200285 | 0.89 | ATR (1.00) | ATRATRIPGAKCYP3A4CYP2C8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3395818-B1 | 2-(MORPHOLIN-4-YL)-1,7-NAPHTHYRIDINES | Bayer Pharma AG (DE) | 2021-09-22 | — | — | EP | disclosed |
| EP-3177619-B1 | 2-(MORPHOLIN-4-YL)-1,7-NAPHTHYRIDINES | Bayer Pharma AG (DE) | 2018-04-25 | — | — | EP | disclosed |