⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28298519 | 0.77 | — | — | |
| SCHEMBL27778073 | 0.76 | — | — | |
| SCHEMBL158670 | 0.69 | — | — | |
| SCHEMBL3264601 | 0.69 | — | — | |
| SCHEMBL3036185 | 0.65 | TSHR (0.35) | — | |
| SCHEMBL15836162 | 0.65 | — | — | |
| SCHEMBL940483 | 0.65 | — | — | |
| SCHEMBL666077 | 0.65 | — | — | |
| SCHEMBL9312420 | 0.65 | — | — | |
| SCHEMBL28123285 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107149591-A | The stable composition and its application method of alkylating agent | 埃科特莱茵药品有限公司 | 2017-09-12 | — | — | CN | disclosed |
| US-20150037395-A1 | TRANSDERMAL HORMONE DELIVERY SYSTEM: COMPOSITIONS AND MTEHODS | AGILE THERAPEUTICS, INC. (US) | 2015-02-05 | — | — | US | disclosed |
| US-8883196-B2 | Transdermal hormone delivery system: compositions and methods | AGILE THERAPEUTICS, INC. (US) | 2014-11-11 | — | — | US | disclosed |
| US-20140072615-A1 | TRANSDERMAL HORMONE DELIVERY SYSTEM: COMPOSITIONS AND METHODS | AGILE THERAPEUTICS, INC. (US) | 2014-03-13 | — | — | US | disclosed |
| US-8221784-B2 | Transdermal hormone delivery system: compositions and methods | AGILE THERAPEUTICS, INC. (US) | 2012-07-17 | — | — | US | disclosed |
| US-8221785-B2 | Transdermal hormone delivery system: compositions and methods | AGILE THERAPEUTICS, INC. (US) | 2012-07-17 | — | — | US | disclosed |
| US-7964564-B2 | Chimeric natriuretic peptides | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2011-06-21 | — | — | US | disclosed |
| CN-102036557-A | Stabilized compositions of alkylating agents and methods of use thereof | YAUPON THERAPEUTICS INC | 2011-04-27 | — | — | CN | disclosed |
| US-20090324697-A1 | TRANSDERMAL HORMONE DELIVERY SYSTEM: COMPOSITIONS AND METHODS | EXELTIS USA, INC. | 2009-12-31 | — | — | US | disclosed |
| US-20090311312-A1 | Transdermal Hormone Delivery System: Compositions And Methods | EXELTIS USA, INC. | 2009-12-17 | — | — | US | disclosed |
| EP-1658029-A4 | TRANSDERMAL HORMONE DELIVERY SYSTEM: COMPOSITIONS AND METHODS | AGILE THERAPEUTICS INC (US) | 2008-04-16 | — | — | EP | disclosed |
| US-20070065495-A1 | Transdermal hormone delivery system: compositions and methods | AGILE THERAPEUTICS, INC. (US) | 2007-03-22 | — | — | US | disclosed |
| US-7091026-B2 | Artificial endonuclease | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2006-08-15 | — | — | US | disclosed |
| EP-1658029-A1 | TRANSDERMAL HORMONE DELIVERY SYSTEM: COMPOSITIONS AND METHODS | Agile Therapeutics, Inc. (US) | 2006-05-24 | — | — | EP | disclosed |
| US-20050059600-A1 | Chimeric natriuretic peptides | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH | 2005-03-17 | — | — | US | disclosed |
| WO-2005002482-A1 | TRANSDERMAL HORMONE DELIVERY SYSTEM: COMPOSITIONS AND METHODS | AGILE THERAPEUTICS, INC. (US) | 2005-01-13 | — | — | WO | disclosed |
| US-20040053901-A1 | A skin permeation enhancer for enhancing absorption of a steroid hormone through the skin, containing an organic solvent, a fatty (C8-C20) alcohol ester of a hydroxy acid, a lower alkyl ester of hydroxy acid and a (C6-C18) fatty acid | EXELTIS USA, INC. | 2004-03-18 | — | — | US | disclosed |
| US-20020146788-A1 | Artificial endonuclease | UNIVERSITY OF IOWA RESEARCH FOUNDATION | 2002-10-10 | — | — | US | disclosed |
| EP-1224313-A1 | ADENO-ASSOCIATED VIRUSES AND USES THEREOF | University of Iowa Research Foundation (US) | 2002-07-24 | — | — | EP | disclosed |
| WO-2001025465-A1 | ADENO-ASSOCIATED VIRUSES AND USES THEREOF | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2001-04-12 | — | — | WO | disclosed |