Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 2/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | CFB | P00751 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1290215 | 0.90 | CYP1A2 (0.39) | NOTUMKDM4EALDH1A1GAAPKM | |
| SCHEMBL20960258 | 0.87 | NOTUM (0.34) | NOTUMKDM4EALDH1A1GAAPKM | |
| SCHEMBL1290187 | 0.86 | NOTUM (0.34) | NOTUMKDM4EALDH1A1GAAPKM | |
| SCHEMBL5421645 | 0.84 | DHODH (0.37) | NOTUMKDM4EALDH1A1GAAPKM | |
| SCHEMBL20083177 | 0.83 | NOTUM (0.33) | NOTUMKDM4EALDH1A1GAAPKM | |
| SCHEMBL1290198 | 0.83 | NOTUM (0.36) | NOTUMKDM4EALDH1A1GAAPKM | |
| SCHEMBL1290058 | 0.83 | KDM4C (0.39) | NOTUMKDM4EALDH1A1GAAPKM | |
| SCHEMBL1290162 | 0.82 | NOTUM (0.37) | NOTUMKDM4EALDH1A1GAAPKM | |
| SCHEMBL12502345 | 0.82 | KDM4E (0.36) | NOTUMKDM4EALDH1A1GAAPKM | |
| SCHEMBL1289991 | 0.82 | BRD4 (0.37) | NOTUMKDM4EALDH1A1GAAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3312176-A1 | ANTIMICROBIAL 4-OXOQUINOLIZINES | Emergent Product Development Gaithersburg Inc. (US) | 2018-04-25 | — | — | EP | disclosed |