⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5036090 | 0.98 | NAPRT (0.39) | — | |
| SCHEMBL28705949 | 0.79 | — | — | |
| SCHEMBL1146338 | 0.77 | — | — | |
| SCHEMBL17447434 | 0.77 | — | — | |
| SCHEMBL31366360 | 0.77 | — | — | |
| SCHEMBL13925527 | 0.77 | — | — | |
| SCHEMBL6989753 | 0.77 | — | — | |
| SCHEMBL344036 | 0.77 | — | — | |
| SCHEMBL844104 | 0.77 | — | — | |
| SCHEMBL30316707 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4615817-A1 | BENZALDEHYDE COMPOUNDS WITH DIRECT POLYMER DESTABILIZING EFFECTS TO TREAT SICKLE CELL DISEASE | Virginia Commonwealth University (US) | 2025-09-17 | — | — | EP | disclosed |
| CN-119930720-A | Application of spinosyn derivative as pesticide | 利民化学有限责任公司 | 2025-05-06 | — | — | CN | disclosed |
| CN-115785180-B | Spinosyn derivative as pesticide, and preparation method and application thereof | 利民化学有限责任公司 | 2025-03-07 | — | — | CN | disclosed |
| US-20250019349-A1 | BENZALDEHYDE COMPOUNDS WITH DIRECT POLYMER DESTABILIZING EFFECTS TO TREAT SICKLE CELL DISEASE | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 2025-01-16 | — | — | US | disclosed |
| US-12065408-B2 | Benzaldehyde compounds with direct polymer destabilizing effects to treat sickle cell disease | VIRGINIA COMMONWEALTH UNIVERISTY (US) | 2024-08-20 | — | — | US | disclosed |
| US-20240174612-A1 | BENZALDEHYDE COMPOUNDS WITH DIRECT POLYMER DESTABILIZING EFFECTS TO TREAT SICKLE CELL DISEASE | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 2024-05-30 | — | — | US | disclosed |
| WO-2024102304-A1 | BENZALDEHYDE COMPOUNDS WITH DIRECT POLYMER DESTABILIZING EFFECTS TO TREAT SICKLE CELL DISEASE | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 2024-05-16 | — | — | WO | disclosed |
| WO-2024102306-A1 | HIGHLY WATER SOLUBLE SCHIFF BASE PRODRUGS OF BENZALDEHYDE ALLOSTERIC MODULATORS | ILLEXCOR HOLDINGS, LLC (US) | 2024-05-16 | — | — | WO | disclosed |
| US-20240109843-A1 | BENZALDEHYDE COMPOUNDS WITH DIRECT POLYMER DESTABILIZING EFFECTS TO TREAT SICKLE CELL DISEASE | KING ABDULAZIZ UNIVERSITY (SA) | 2024-04-04 | — | — | US | disclosed |
| CN-117510338-A | Natural naphthoquinone derivative and preparation method and application thereof | 贵州大学 | 2024-02-06 | — | — | CN | disclosed |
| WO-2006128693-A2 | 2 -OXO-I -PYRROLIDINE DERIVATIVES/ PROCESSES FOR PREPARING THEM AND THEIR THERAPEUTIC USE ON THE CENTRAL NERVOUS SYSTEM | UCB PHARMA, S.A. (BE) | 2006-12-07 | — | — | WO | disclosed |
| WO-2006128692-A2 | 2-OXO-1-PYRROLIDINE DERIVATIVES AND THEIR THERAPEUTIC USE ON THE CENTRAL NERVOUS SYSTEM | UCB PHARMA, S.A. (BE) | 2006-12-07 | — | — | WO | disclosed |
| CN-1665791-A | Quinazoline derivatives | HOFFMANN LA ROCHE (CH) | 2005-09-07 | — | — | CN | disclosed |
| EP-1560816-A1 | QUINAZOLINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2005-08-10 | — | — | EP | disclosed |
| US-20050049413-A1 | Quinoline derivatives | MUELLER WERNER (CH) | 2005-03-03 | — | — | US | disclosed |
| US-6818767-B2 | NEUROPEPTIDE Y (NPY) ANTAGONISTS FOR THE TREATMENT OR PREVENTION OF ARTHRITIS, CARDIOVASCULAR DISEASES, DIABETES, RENAL FAILURE, EATING DISORDERS, OR OBESITY | HOFFMANN-LA ROCHE INC. | 2004-11-16 | — | — | US | disclosed |
| US-20040029901-A1 | Quinazoline derivatives | HOFFMANN-LA ROCHE INC. | 2004-02-12 | — | — | US | disclosed |
| WO-2004005265-A1 | QUINAZOLINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2004-01-15 | — | — | WO | disclosed |
| US-20020198194-A1 | Quinoline derivatives | HOFFMANN-LA ROCHE INC. | 2002-12-26 | — | — | US | disclosed |
| US-5298507-A | Insecticides | NIHON BAYER AGROCHEM K.K. (JP) | 1994-03-29 | — | — | US | disclosed |