Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20086391 | 1.00 | GRIN1 (0.83) | GRIN1GRIN2B | |
| SCHEMBL17633234 | 0.91 | GRIN1 (1.00) | GRIN1GRIN2B | |
| SCHEMBL20090996 | 0.91 | GRIN1 (1.00) | GRIN1GRIN2B | |
| SCHEMBL17633401 | 0.91 | GRIN1 (1.00) | GRIN1GRIN2B | |
| SCHEMBL17633233 | 0.91 | GRIN1 (1.00) | GRIN1GRIN2B | |
| SCHEMBL24136373 | 0.91 | GRIN1 (1.00) | GRIN1GRIN2B | |
| SCHEMBL17643277 | 0.88 | GRIN1 (1.00) | GRIN1GRIN2B | |
| SCHEMBL20983486 | 0.88 | GRIN1 (1.00) | GRIN1GRIN2B | |
| SCHEMBL17643120 | 0.88 | GRIN1 (1.00) | GRIN1GRIN2B | |
| SCHEMBL24136375 | 0.88 | GRIN1 (1.00) | GRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180111902-A1 | N-ALKYLARYL-5-OXYARYL-OCTAHYDRO-CYCLOPENTA[C]PYRROLE NEGATIVE ALLOSTERIC MODULATORS OF NR2B | LUC THERAPEUTICS, INC. (US) | 2018-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180111902-A1 | N-ALKYLARYL-5-OXYARYL-OCTAHYDRO-CYCLOPENTA[C]PYRROLE NEGATIVE ALLOSTERIC MODULATORS OF NR2B | OXER1, OPRL1, OXGR1 | GRIN1 31/4885GRIN2B 25/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.