⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5530809 | 1.00 | — | — | |
| SCHEMBL12712884 | 1.00 | — | — | |
| SCHEMBL11319639 | 0.75 | — | — | |
| SCHEMBL1400146 | 0.70 | — | — | |
| SCHEMBL3729692 | 0.69 | — | — | |
| SCHEMBL6360894 | 0.69 | — | — | |
| SCHEMBL28269877 | 0.69 | — | — | |
| SCHEMBL12712929 | 0.67 | — | — | |
| SCHEMBL19014757 | 0.67 | — | — | |
| SCHEMBL814123 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4252848-A2 | OXYSTEROLS AND METHODS OF USE THEREOF | Sage Therapeutics, Inc. (US) | 2023-10-04 | — | — | EP | disclosed |
| US-20210380631-A1 | OXYSTEROLS AND METHODS OF USE THEREOF | SAGE THERAPEUTICS, INC. | 2021-12-09 | — | — | US | disclosed |
| US-11149054-B2 | Oxysterols and methods of use thereof | SAGE THERAPEUTICS, INC. (US) | 2021-10-19 | — | — | US | disclosed |
| US-20190248829-A1 | OXYSTEROLS AND METHODS OF USE THEREOF | SAGE THERAPEUTICS, INC. (US) | 2019-08-15 | — | — | US | disclosed |
| WO-2018075699-A1 | OXYSTEROLS AND METHODS OF USE THEREOF | SAGE THERAPEUTICS, INC. (US) | 2018-04-26 | — | — | WO | disclosed |