SCHEMBL20089073

SCHEMBL20089073

c1ccc(C2(c3ccccc3)c3ccccc3-c3ccc(N(c4ccc5c(c4)C(c4ccccc4)(c4ccc6c(c4)sc4ccccc46)c4ccccc4-5)c4ccc5ccccc5c4)cc32)cc1

nearest known ligand 0.32

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
LMNA P02545 1/20 0.32
OPRK1 P41145 1/20 0.32
KMT2A Q03164 1/20 0.32
ALDH1A1 P00352 1/20 0.32
HPGD P15428 1/20 0.32
RAB9A P51151 1/20 0.32
ESR1 P03372 1/20 0.31
ESR2 Q92731 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20089080 0.94 KDM4E (0.32) MAPTSMN1; SMN2KDM4EMEN1LMNA
SCHEMBL18118738 0.92 S1PR4 (0.31)
SCHEMBL18118736 0.91 MAPT (0.35) MAPTSMN1; SMN2KDM4EMEN1LMNA
SCHEMBL20089051 0.91 MAPT (0.35) MAPTSMN1; SMN2KDM4EMEN1LMNA
SCHEMBL20466627 0.89 MAPT (0.37) MAPTSMN1; SMN2KDM4EMEN1LMNA
SCHEMBL18118718 0.88 MAPT (0.33) MAPTSMN1; SMN2KDM4EMEN1LMNA
SCHEMBL24883155 0.88 MAPT (0.35) MAPTSMN1; SMN2KDM4EMEN1LMNA
SCHEMBL21392685 0.88 MAPT (0.36) MAPTSMN1; SMN2KDM4EMEN1LMNA
SCHEMBL18118719 0.88 MAPT (0.31) MAPTSMN1; SMN2KDM4EMEN1LMNA
SCHEMBL18118711 0.88 MAPT (0.32) MAPTSMN1; SMN2KDM4EMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10580993-B2 Amine compound and organic electroluminescence device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2020-03-03 US disclosed
US-20180114906-A1 AMINE COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2018-04-26 US disclosed
US-20180114906-A1 AMINE COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2018-04-26 US disclosed