Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | PER2 | O15055 | 2/20 | 0.37 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19762326 | 0.92 | POLB (0.38) | POLBKMT2AMEN1PIK3CDTSHR | |
| SCHEMBL21727226 | 0.88 | PIK3CD (0.42) | POLBKMT2AMEN1PIK3CDTSHR | |
| SCHEMBL28666358 | 0.87 | POLB (0.41) | POLBKMT2AMEN1PIK3CDTSHR | |
| SCHEMBL22000766 | 0.85 | POLB (0.38) | POLBKMT2AMEN1PIK3CDTSHR | |
| SCHEMBL22000371 | 0.83 | KMT2A (0.40) | POLBKMT2AMEN1PIK3CDTSHR | |
| SCHEMBL19514128 | 0.81 | KMT2A (0.50) | POLBKMT2AMEN1PIK3CDTSHR | |
| SCHEMBL7937319 | 0.79 | KMT2A (0.51) | POLBKMT2AMEN1PIK3CDTSHR | |
| SCHEMBL12056407 | 0.78 | PIK3CD (0.56) | POLBKMT2AMEN1PIK3CDTSHR | |
| SCHEMBL20687601 | 0.77 | KMT2A (0.48) | POLBKMT2AMEN1PIK3CDTSHR | |
| SCHEMBL2490366 | 0.76 | POLB (0.45) | POLBKMT2AMEN1PIK3CDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180112100-A1 | COATING COMPOSITIONS CONTAINING LACTAM-FUNCTIONALIZED POLYMER | HERCULES LLC (US) | 2018-04-26 | — | — | US | disclosed |