Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 20/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | TDO2 | P48775 | 1/20 | 0.46 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23066851 | 0.91 | IDO1 (0.55) | IDO1CYP3A4CYP2C9TDO2IDO2 | |
| SCHEMBL20090569 | 0.91 | IDO1 (0.55) | IDO1CYP3A4CYP2C9TDO2IDO2 | |
| SCHEMBL23066815 | 0.89 | IDO1 (0.60) | IDO1 | |
| SCHEMBL23066814 | 0.89 | IDO1 (0.60) | IDO1 | |
| SCHEMBL20199308 | 0.88 | IDO1 (0.52) | IDO1CYP3A4CYP2C9TDO2IDO2 | |
| SCHEMBL23066818 | 0.88 | IDO1 (0.51) | IDO1CYP3A4CYP2C9TDO2IDO2 | |
| SCHEMBL20198869 | 0.88 | IDO1 (0.51) | IDO1CYP3A4CYP2C9TDO2IDO2 | |
| SCHEMBL20090651 | 0.87 | IDO1 (0.58) | IDO1 | |
| SCHEMBL28925346 | 0.87 | IDO1 (0.71) | IDO1 | |
| SCHEMBL23066808 | 0.87 | IDO1 (0.58) | IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018072697-A1 | OXADIAZOLE RING-CONTAINING COMPOUND, PREPARATION METHOD THEREFOR, AND INTERMEDIATE, COMPOSITE, AND APPLICATION THEREOF | 上海医药集团股份有限公司 | 2018-04-26 | — | — | WO | disclosed |