SCHEMBL2009058

SCHEMBL2009058

Oc1ccc(C(I)c2ccccc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.52
TDO2 P48775 1/20 0.52
TDP1 Q9NUW8 2/20 0.48
CA12 O43570 2/20 0.48
CA1 P00915 2/20 0.48
CA2 P00918 2/20 0.48
CA3 P07451 2/20 0.48
CA4 P22748 2/20 0.48
CA9 Q16790 2/20 0.48
CA14 Q9ULX7 2/20 0.48
GLA P06280 1/20 0.48
MMP3 P08254 1/20 0.46
BCL2L1 Q07817 1/20 0.46
ALDH1A1 P00352 3/20 0.44
LMNA P02545 3/20 0.44
HSD17B10 Q99714 3/20 0.44
ESR1 P03372 7/20 0.44
ESR2 Q92731 7/20 0.44
PDCD1 Q15116 1/20 0.44
CD274 Q9NZQ7 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6913680 0.89 ESR1 (0.52) TDP1CA12CA1CA2CA3
SCHEMBL873428 0.84 DPP4 (0.47) LMNAMTORRAB9ACES2
SCHEMBL982047 0.79 IDO1 (0.56) IDO1TDO2TDP1CA12CA1
SCHEMBL36791 0.79 IDO1 (0.56) IDO1TDO2TDP1CA12CA1
SCHEMBL14163315 0.79 IDO1 (0.56) IDO1TDO2TDP1CA12CA1
SCHEMBL17995329 0.79 IDO1 (0.56) IDO1TDO2TDP1CA12CA1
SCHEMBL503028 0.79 IDO1 (0.56) IDO1TDO2TDP1CA12CA1
SCHEMBL19314626 0.79 IDO1 (0.56) IDO1TDO2TDP1CA12CA1
SCHEMBL22694327 0.79 IDO1 (0.56) IDO1TDO2TDP1CA12CA1
SCHEMBL477709 0.77 CYP17A1 (0.55) IDO1TDO2TDP1CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2513217-A1 SCRATCH-RESISTANT, IMPACT-RESISTANT POLYCARBONATE MOULDING COMPOSITIONS WITH GOOD MECHANICAL PROPERTIES I Bayer Intellectual Property GmbH (DE) 2012-10-24 EP disclosed
WO-2011073289-A1 SCRATCH-RESISTANT, IMPACT-RESISTANT POLYCARBONATE MOULDING COMPOSITIONS WITH GOOD MECHANICAL PROPERTIES I BAYER MATERIALSCIENCE AG (DE) 2011-06-23 WO disclosed