SCHEMBL20090737

SCHEMBL20090737

C#Cc1cc(N/C(=N\O)c2nonc2NCCSC)ccc1F

nearest known ligand 0.41

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 20/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30141344 1.00 IDO1 (0.41) IDO1
SCHEMBL20199306 0.90 IDO1 (0.41) IDO1
SCHEMBL19133468 0.85 IDO1 (0.52) IDO1
SCHEMBL19158107 0.85 IDO1 (0.52) IDO1
SCHEMBL23066860 0.85 IDO1 (0.46) IDO1
SCHEMBL20199011 0.85 IDO1 (0.46) IDO1
SCHEMBL20090601 0.85 IDO1 (0.49) IDO1
SCHEMBL23066855 0.85 IDO1 (0.49) IDO1
SCHEMBL29042716 0.84 IDO1 (0.57) IDO1
SCHEMBL30449667 0.84 IDO1 (0.57) IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107954999-B Oxadiazole ring-containing compound, preparation method, intermediate, composition and application 上海医药集团股份有限公司 2023-01-24 CN disclosed
WO-2018072697-A1 OXADIAZOLE RING-CONTAINING COMPOUND, PREPARATION METHOD THEREFOR, AND INTERMEDIATE, COMPOSITE, AND APPLICATION THEREOF 上海医药集团股份有限公司 2018-04-26 WO disclosed