⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14685486 | 0.74 | — | — | |
| SCHEMBL14685616 | 0.74 | — | — | |
| SCHEMBL8266325 | 0.74 | — | — | |
| SCHEMBL21401201 | 0.71 | — | — | |
| SCHEMBL22826713 | 0.69 | — | — | |
| SCHEMBL20146188 | 0.69 | — | — | |
| SCHEMBL19426843 | 0.69 | — | — | |
| SCHEMBL29928493 | 0.67 | — | — | |
| SCHEMBL21226686 | 0.65 | — | — | |
| SCHEMBL18597355 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230012362-A1 | WDR5 INHIBITORS AND MODULATORS | VANDERBILT UNIVERSITY | 2023-01-12 | — | — | US | disclosed |
| EP-3636644-A1 | MESOIONIC IMIDAZOPYRIDINES AS INSECTICIDES | Bayer Aktiengesellschaft (DE) | 2020-04-15 | — | — | EP | disclosed |
| US-10421751-B2 | Dihydro-2H-benzo[b][1,4]oxazine sulfonamide and related compounds for use as agonists of RORγ and the treatment of disease | LYCERA CORPORATION (US) | 2019-09-24 | — | — | US | disclosed |
| US-20180111922-A1 | DIHYDRO-2H-BENZO[b][1,4]OXAZINE SULFONAMIDE AND RELATED COMPOUNDS FOR USE AS AGONISTS OF RORy AND THE TREATEMENT OF DISEASE | LYCERA CORPORATION | 2018-04-26 | — | — | US | disclosed |