SCHEMBL2009132

SCHEMBL2009132

[CH2]C(COC(=O)C=C)OC(=O)C=C

nearest known ligand 0.57

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.57
ALDH1A1 P00352 4/20 0.45
TP53 P04637 3/20 0.45
HIF1A Q16665 3/20 0.45
CYP3A4 P08684 2/20 0.45
HSD17B10 Q99714 1/20 0.45
MAPK1 P28482 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
HPGD P15428 1/20 0.41
THRB P10828 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27561682 0.83 TSHR (0.57) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL2335557 0.80 TSHR (0.59) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL700993 0.80 TSHR (0.59) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL8127216 0.80 TSHR (0.59) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL15455068 0.79 TSHR (0.64) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL4431912 0.78 TSHR (0.57) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL9362685 0.78 TSHR (0.57) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL212283 0.77
SCHEMBL866028 0.77
SCHEMBL2011391 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7963660-B2 Antiglare hard-coated film NITTO DENKO CORPORATION (JP) 2011-06-21 US disclosed
US-20090086326-A1 ANTIGLARE HARD-COATED FILM NITTO DENKO CORPORATION (JP) 2009-04-02 US disclosed
US-5235096-A Hydroxybenzenesulfone compound having a polymerizable group and process for producing the same FUJI PHOTO FILM CO., LTD. (JP) 1993-08-10 US disclosed