Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 20/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20092563 | 0.93 | TYK2 (0.48) | TYK2 | |
| SCHEMBL20093188 | 0.89 | TYK2 (0.48) | TYK2 | |
| SCHEMBL20093299 | 0.88 | TYK2 (0.56) | TYK2 | |
| SCHEMBL20092557 | 0.86 | TYK2 (0.54) | TYK2 | |
| SCHEMBL20092105 | 0.85 | TYK2 (0.55) | TYK2 | |
| SCHEMBL20092795 | 0.85 | TYK2 (0.55) | TYK2 | |
| SCHEMBL20093113 | 0.85 | TYK2 (0.43) | TYK2 | |
| SCHEMBL20093115 | 0.84 | TYK2 (0.56) | TYK2 | |
| SCHEMBL20093077 | 0.83 | TYK2 (0.45) | TYK2 | |
| SCHEMBL20092555 | 0.83 | ATR (0.38) | TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018075937-A1 | TYK2 INHIBITORS AND USES THEREOF | NIMBUS LAKSHMI, INC. (US) | 2018-04-26 | — | — | WO | disclosed |