Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR4 | P22455 | 20/20 | 0.80 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.80 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.80 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.80 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.80 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.80 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.62 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20094005 | 0.90 | FGFR4 (0.86) | FGFR4FGFR1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL20094119 | 0.90 | FGFR4 (0.74) | FGFR4FGFR1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL18131722 | 0.89 | FGFR4 (1.00) | FGFR4FGFR1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL20094116 | 0.86 | FGFR4 (0.69) | FGFR4FGFR1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL20093934 | 0.85 | FGFR4 (0.89) | FGFR4FGFR1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL20094004 | 0.85 | FGFR4 (1.00) | FGFR4FGFR1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL18131746 | 0.84 | FGFR4 (0.84) | FGFR4FGFR1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL28561621 | 0.82 | FGFR4 (1.00) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL18131723 | 0.82 | FGFR4 (1.00) | FGFR4FGFR1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL18131734 | 0.82 | FGFR4 (0.87) | FGFR4FGFR1CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018072707-A1 | AROMATIC ETHER DERIVATIVE, PREPARATION METHOD THEREFOR, AND MEDICAL APPLICATIONS THEREOF | 保诺科技（北京）有限公司 | 2018-04-26 | — | — | WO | disclosed |