Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 20/20 | 0.60 |
| ▸ | FABP1 | P07148 | 6/20 | 0.59 |
| ▸ | FABP4 | P15090 | 1/20 | 0.57 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19628515 | 0.84 | NR1H4 (0.59) | NR1H4FABP1FABP4HSD17B13 | |
| SCHEMBL19230549 | 0.83 | NR1H4 (0.58) | NR1H4FABP1FABP4HSD17B13 | |
| SCHEMBL1096115 | 0.82 | NR1H4 (0.58) | NR1H4FABP1FABP4HSD17B13 | |
| SCHEMBL21912462 | 0.81 | NR1H4 (0.57) | NR1H4FABP1FABP4HSD17B13 | |
| SCHEMBL20419570 | 0.81 | NR1H4 (0.57) | NR1H4FABP1FABP4HSD17B13 | |
| SCHEMBL22789950 | 0.81 | NR1H4 (0.55) | NR1H4FABP1FABP4HSD17B13 | |
| SCHEMBL29345034 | 0.81 | NR1H4 (0.62) | NR1H4FABP1FABP4HSD17B13 | |
| SCHEMBL28416415 | 0.81 | NR1H4 (0.62) | NR1H4FABP1FABP4HSD17B13 | |
| SCHEMBL21703707 | 0.81 | NR1H4 (0.62) | NR1H4FABP1FABP4HSD17B13 | |
| SCHEMBL21264346 | 0.81 | NR1H4 (0.62) | NR1H4FABP1FABP4HSD17B13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018075207-A1 | HETEROCYCLIC FXR MODULATORS | HEPAGENE THERAPEUTICS, INC. (VG) | 2018-04-26 | — | — | WO | disclosed |