Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 20/20 | 0.70 |
| ▸ | LIFR | P42702 | 1/20 | 0.56 |
| ▸ | PPARD | Q03181 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19499324 | 0.87 | NR1H4 (0.72) | NR1H4LIFRPPARD | |
| SCHEMBL12168743 | 0.84 | NR1H4 (0.67) | NR1H4LIFRPPARD | |
| SCHEMBL1179026 | 0.84 | NR1H4 (0.67) | NR1H4LIFRPPARD | |
| SCHEMBL23773958 | 0.84 | NR1H4 (0.67) | NR1H4LIFRPPARD | |
| SCHEMBL1097396 | 0.83 | NR1H4 (0.66) | NR1H4LIFRPPARD | |
| SCHEMBL4610788 | 0.83 | NR1H4 (0.66) | NR1H4LIFRPPARD | |
| SCHEMBL1096077 | 0.83 | NR1H4 (0.70) | NR1H4LIFRPPARD | |
| SCHEMBL21340005 | 0.83 | NR1H4 (0.66) | NR1H4LIFRPPARD | |
| SCHEMBL24425708 | 0.83 | NR1H4 (1.00) | NR1H4LIFRPPARD | |
| SCHEMBL26965118 | 0.83 | NR1H4 (0.66) | NR1H4LIFRPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018075207-A1 | HETEROCYCLIC FXR MODULATORS | HEPAGENE THERAPEUTICS, INC. (VG) | 2018-04-26 | — | — | WO | disclosed |