Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCNN1A | P37088 | 3/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20094903 | 0.97 | SCNN1A (0.36) | SCNN1APARP1CA1CA2ACHE | |
| SCHEMBL19820077 | 0.96 | SCNN1A (0.36) | SCNN1A | |
| SCHEMBL19820056 | 0.91 | SCNN1A (0.37) | SCNN1ACA1CA2 | |
| SCHEMBL20094990 | 0.89 | SCNN1A (0.41) | SCNN1ACA1CA2 | |
| SCHEMBL19820054 | 0.88 | SCNN1A (0.39) | SCNN1ACA1CA2 | |
| SCHEMBL19820015 | 0.87 | SCNN1A (0.37) | SCNN1ACA1CA2 | |
| SCHEMBL10115947 | 0.87 | SCNN1A (0.42) | SCNN1A | |
| SCHEMBL19820041 | 0.86 | SCNN1A (0.43) | SCNN1ACA1CA2 | |
| SCHEMBL19820044 | 0.86 | SCNN1A (0.43) | SCNN1ACA1CA2 | |
| SCHEMBL19820088 | 0.86 | SCNN1A (0.43) | SCNN1ACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180111907-A1 | DENDRIMER LIKE AMINO AMIDES POSSESSING SODIUM CHANNEL BLOCKER ACTIVITY FOR THE TREATMENT OF DRY EYE AND OTHER MUCOSAL DISEASES | PARION SCIENCES, INC. | 2018-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180111907-A1 | DENDRIMER LIKE AMINO AMIDES POSSESSING SODIUM CHANNEL BLOCKER ACTIVITY FOR THE TREATMENT OF DRY EYE AND OTHER MUCOSAL DISEASES | SCNN1B, SCNN1A, SCNN1G | SCNN1A 2/4885PARP1 3666/4885CA1 1404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.