Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 20/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | VHL | P40337 | 6/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20095447 | 1.00 | NAMPT (0.46) | NAMPTCYP3A4CYP2C9VHL | |
| SCHEMBL21470809 | 0.96 | NAMPT (0.46) | NAMPTCYP3A4CYP2C9VHL | |
| SCHEMBL21470960 | 0.96 | NAMPT (0.46) | NAMPTCYP3A4CYP2C9VHL | |
| SCHEMBL20095465 | 0.90 | NAMPT (0.46) | NAMPTCYP3A4CYP2C9VHL | |
| SCHEMBL20095603 | 0.90 | NAMPT (0.54) | NAMPTCYP3A4CYP2C9VHL | |
| SCHEMBL20095470 | 0.90 | NAMPT (0.45) | NAMPTCYP3A4CYP2C9VHL | |
| SCHEMBL27025440 | 0.90 | NAMPT (0.48) | NAMPTCYP3A4CYP2C9VHL | |
| SCHEMBL20095312 | 0.90 | NAMPT (0.48) | NAMPTCYP3A4CYP2C9VHL | |
| SCHEMBL20095311 | 0.90 | NAMPT (0.48) | NAMPTCYP3A4CYP2C9VHL | |
| SCHEMBL21470910 | 0.86 | NAMPT (0.46) | NAMPTCYP3A4CYP2C9VHL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018075600-A1 | TARGETED DELIVERY OF NICOTINAMIDE ADENINE DINUCLEOTIDE SALVAGE PATHWAY INHIBITORS | SEATTLE GENETICS, INC. (US) | 2018-04-26 | — | — | WO | disclosed |