SCHEMBL20095459

SCHEMBL20095459

CCN(CCON(C(=O)CCCCCCNc1c(Nc2ccncc2)c(=O)c1=O)C1CCCCC1)C(=O)c1cccc(NCc2ccc(OC3CCCC(C(=O)O)O3)c(NC(=O)CCNC)c2)c1

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
NAMPT P43490 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20095401 0.88 NAMPT (0.30) NAMPT
SCHEMBL20095471 0.88 NAMPT (0.31) NAMPT
SCHEMBL21462020 0.81 NAMPT (0.38) NAMPT
SCHEMBL20095453 0.81
SCHEMBL20095784 0.78 NAMPT (0.38) NAMPT
SCHEMBL20095323 0.77 NAMPT (0.36) NAMPT
SCHEMBL21462026 0.76
SCHEMBL20095399 0.76
SCHEMBL21461994 0.75
SCHEMBL21462013 0.75 NAMPT (0.41) NAMPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018075600-A1 TARGETED DELIVERY OF NICOTINAMIDE ADENINE DINUCLEOTIDE SALVAGE PATHWAY INHIBITORS SEATTLE GENETICS, INC. (US) 2018-04-26 WO disclosed