Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1C | Q13936 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7114292 | 0.77 | — | — | |
| SCHEMBL20095596 | 0.75 | — | — | |
| SCHEMBL7114265 | 0.75 | HRH4 (0.39) | — | |
| SCHEMBL20096211 | 0.74 | — | — | |
| SCHEMBL20096219 | 0.73 | CACNA1C (0.30) | CACNA1C | |
| SCHEMBL9949828 | 0.73 | HRH4 (0.42) | — | |
| SCHEMBL7121348 | 0.73 | HRH4 (0.42) | — | |
| SCHEMBL803958 | 0.73 | HRH4 (0.42) | — | |
| SCHEMBL20063776 | 0.72 | SCN9A (0.35) | — | |
| SCHEMBL20073031 | 0.72 | SCN9A (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018072602-A1 | THERAPEUTIC COMPOUNDS AND METHODS OF USE THEREOF | GENENTECH, INC. (US) | 2018-04-26 | — | — | WO | disclosed |