Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20095773 | 1.00 | SCN9A (0.35) | SCN9A | |
| SCHEMBL20095836 | 0.85 | — | — | |
| SCHEMBL20095826 | 0.85 | — | — | |
| SCHEMBL20095799 | 0.83 | SCN9A (0.39) | SCN9A | |
| SCHEMBL20063951 | 0.82 | SCN9A (0.30) | SCN9A | |
| SCHEMBL20063367 | 0.82 | SCN9A (0.36) | SCN9A | |
| SCHEMBL20063402 | 0.82 | SCN9A (0.36) | SCN9A | |
| SCHEMBL20063397 | 0.82 | SCN9A (0.36) | SCN9A | |
| SCHEMBL20072933 | 0.81 | SCN9A (0.34) | SCN9A | |
| SCHEMBL20072866 | 0.81 | SCN9A (0.34) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018072602-A1 | THERAPEUTIC COMPOUNDS AND METHODS OF USE THEREOF | GENENTECH, INC. (US) | 2018-04-26 | — | — | WO | disclosed |