Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 20/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20063692 | 1.00 | SCN9A (0.47) | SCN9A | |
| SCHEMBL20063697 | 0.93 | SCN9A (0.46) | SCN9A | |
| SCHEMBL20063743 | 0.92 | SCN9A (0.57) | SCN9A | |
| SCHEMBL20063676 | 0.91 | SCN9A (0.44) | SCN9A | |
| SCHEMBL20063711 | 0.91 | SCN9A (0.38) | SCN9A | |
| SCHEMBL20063698 | 0.91 | SCN9A (0.55) | SCN9A | |
| SCHEMBL20095530 | 0.91 | SCN9A (0.55) | SCN9A | |
| SCHEMBL20063677 | 0.91 | SCN9A (0.55) | SCN9A | |
| SCHEMBL20063739 | 0.90 | SCN9A (0.55) | SCN9A | |
| SCHEMBL20063694 | 0.90 | SCN9A (0.44) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018072602-A1 | THERAPEUTIC COMPOUNDS AND METHODS OF USE THEREOF | GENENTECH, INC. (US) | 2018-04-26 | — | — | WO | disclosed |