Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GBA1 | P04062 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | HRH2 | P25021 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29741328 | 1.00 | AAK1 (0.46) | AAK1PIM1PIM2LMNAGBA1 | |
| SCHEMBL21293969 | 1.00 | AAK1 (0.46) | AAK1PIM1PIM2LMNAGBA1 | |
| SCHEMBL20094079 | 1.00 | AAK1 (0.46) | AAK1PIM1PIM2LMNAGBA1 | |
| SCHEMBL459719 | 0.92 | AAK1 (0.48) | AAK1PIM1PIM2ALOX15KDM4E | |
| SCHEMBL29502212 | 0.92 | AAK1 (0.48) | AAK1PIM1PIM2ALOX15KDM4E | |
| SCHEMBL14247510 | 0.87 | PIM1 (0.45) | AAK1PIM1PIM2LMNAGBA1 | |
| SCHEMBL14247508 | 0.87 | PIM1 (0.45) | AAK1PIM1PIM2LMNAGBA1 | |
| SCHEMBL2946261 | 0.85 | MAPT (0.56) | AAK1PIM1LMNAALOX15KDM4E | |
| SCHEMBL17678063 | 0.85 | MAPT (0.51) | AAK1PIM1LMNAALOX15KDM4E | |
| SCHEMBL20096170 | 0.84 | AAK1 (0.48) | AAK1ALOX15KDM4EGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3529240-B1 | PHARMACEUTICAL COMPOUNDS | CELLCENTRIC LTD (GB) | 2020-08-05 | — | — | EP | disclosed |
| WO-2018073587-A1 | PHARMACEUTICAL COMPOUNDS | CELLCENTRIC LTD (GB) | 2018-04-26 | — | — | WO | disclosed |