SCHEMBL200966

SCHEMBL200966

CO[Si](CC1CC2C=CC1C2)(OC)OC

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 9/20 0.42
ALDH1A1 P00352 3/20 0.42
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
HTT P42858 1/20 0.35
TSHR P16473 1/20 0.34
POLB P06746 1/20 0.33
ALOX15 P16050 1/20 0.33
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C19 P33261 1/20 0.31
ATM Q13315 1/20 0.31
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL200265 0.83 KDM4E (0.41) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL6063905 0.83 KDM4E (0.41) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL115037 0.81 KDM4E (0.40) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL15802761 0.81 KDM4E (0.40) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL1878286 0.81 KDM4E (0.44) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL16335885 0.81 KDM4E (0.40) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL6064177 0.80 KDM4E (0.42) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL6063193 0.80 KDM4E (0.42) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL6064089 0.79 KDM4E (0.38) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL6064453 0.79 KDM4E (0.38) KDM4EALDH1A1MEN1KMT2AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9417477-B2 Polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2016-08-16 US disclosed
US-20150146140-A1 POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2015-05-28 US disclosed
EP-1223195-B1 Thermoplastic resin composition and shaped articles thereof JSR CORP (JP) 2012-03-14 EP disclosed
US-8089593-B2 Optical resin film, optical compensation sheet, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2012-01-03 US disclosed
US-7719644-B2 Optical compensation sheet, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2010-05-18 US disclosed
CN-100478391-C Cycloolefen addition copolymer composition and cross-linked material JSR CORP (JP) 2009-04-15 CN disclosed
US-20090033835-A1 Optical Compensation Sheet, Polarizing Plate and Liquid Crystal Display FUJIFILM CORPORATION (JP) 2009-02-05 US disclosed
US-20080284957-A1 Optical Resin Film, Optical Compensation Sheet, Polarizing Plate and Liquid Crystal Display FUJIFILM CORPORATION (JP) 2008-11-20 US disclosed
US-20080143928-A1 Polarizing Plate and Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2008-06-19 US disclosed
EP-1364975-B1 PROCESSES FOR PRODUCING CYCLOOLEFIN ADDITION POLYMER JSR CORP (JP) 2008-04-30 EP disclosed
US-20040106740-A1 Resin film and applications thereof JSR CORPORATION (JP) 2004-06-03 US disclosed
EP-1195397-B1 Composition of cyclic olefin addition copolymer and cross-linked material JSR CORP (JP) 2004-04-14 EP disclosed
US-20040063873-A1 Processes for producing cycloolefin addition polymer JSR CORPORATION (JP) 2004-04-01 US disclosed
EP-1364975-A1 PROCESSES FOR PRODUCING CYCLOOLEFIN ADDITION POLYMER JSR Corporation (JP) 2003-11-26 EP disclosed
US-6562908-B2 Blend of rubber reinforced thermoplastic resins, acrylic resins and thermoplastic norbornene resins; heat resistance, strength, processability, and laser marking properties JSR CORPORATION (JP) 2003-05-13 US disclosed
US-20020128392-A1 Thermoplastic resin composition and shaped articles thereof JSR CORPORATION (JP) 2002-09-12 US disclosed
EP-1223195-A2 Thermoplastic resin composition and shaped articles thereof JSR Corporation (JP) 2002-07-17 EP disclosed
CN-1347939-A Cycloolefen addition copolymer composition and cross-linked material JSR CORP (JP) 2002-05-08 CN disclosed
US-20020042461-A1 Composition of cyclic olefin addition copolymer and cross-linked material JSR CORPORATION (JP) 2002-04-11 US disclosed
EP-1195397-A1 Composition of cyclic olefin addition copolymer and cross-linked material JSR Corporation (JP) 2002-04-10 EP disclosed