Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 4/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.60 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.59 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.59 |
| ▸ | PI4KA | P42356 | 2/20 | 0.58 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.58 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.58 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.55 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.55 |
| ▸ | NT5E | P21589 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20096689 | 0.89 | ADORA2A (0.66) | ADORA2AALDH1A1FGFR1ADORA1ADORA2B | |
| SCHEMBL8207464 | 0.88 | ADORA2A (0.75) | ADORA2AALDH1A1FGFR1ADORA1ADORA2B | |
| SCHEMBL9885880 | 0.83 | ADORA2A (0.69) | ADORA2AADORA1ADORA2BPI4KAPI4K2B | |
| SCHEMBL8193948 | 0.82 | ADORA2A (0.59) | ADORA2AALDH1A1FGFR1ADORA1ADORA2B | |
| SCHEMBL8186532 | 0.82 | ADORA2A (0.59) | ADORA2AALDH1A1FGFR1ADORA1ADORA2B | |
| SCHEMBL8220260 | 0.82 | ADORA2A (0.59) | ADORA2AALDH1A1FGFR1ADORA1ADORA2B | |
| SCHEMBL23228230 | 0.82 | ADORA2A (0.88) | ADORA2AALDH1A1FGFR1ADORA1ADORA2B | |
| SCHEMBL21469779 | 0.82 | ADORA2A (0.88) | ADORA2AALDH1A1FGFR1ADORA1ADORA2B | |
| SCHEMBL1741560 | 0.82 | ADORA2A (0.88) | ADORA2AALDH1A1FGFR1ADORA1ADORA2B | |
| SCHEMBL9484927 | 0.82 | ADORA2A (0.88) | ADORA2AALDH1A1FGFR1ADORA1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018075947-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF RNA VIRAL INFECTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-04-26 | — | — | WO | disclosed |