Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | DOT1L | Q8TEK3 | 3/20 | 0.53 |
| ▸ | AMD1 | P17707 | 1/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.52 |
| ▸ | DPP4 | P27487 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.52 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.52 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.52 |
| ▸ | GAPDH | P04406 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.52 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.52 |
| ▸ | STAT6 | P42226 | 1/20 | 0.52 |
| ▸ | PI4KA | P42356 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.52 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21311417 | 0.92 | ATM (0.56) | ATMDOT1LAMD1ADORA1DPP4 | |
| SCHEMBL20097001 | 0.85 | DOT1L (0.61) | DOT1LAMD1KMT2ANNMTAHCY | |
| SCHEMBL21311155 | 0.81 | DOT1L (0.60) | ATMDOT1LADORA1DPP4MEN1 | |
| SCHEMBL20096930 | 0.81 | DOT1L (0.60) | ATMDOT1LADORA1DPP4MEN1 | |
| SCHEMBL20096943 | 0.79 | DOT1L (0.66) | ATMDOT1LAMD1ADORA1DPP4 | |
| SCHEMBL21311471 | 0.79 | ADORA2A (0.33) | ATMDOT1LSLC28A1ADORA3ADORA2A | |
| SCHEMBL17568775 | 0.79 | EHMT1 (0.70) | DOT1LAMD1ADORA1DPP4MEN1 | |
| SCHEMBL15395392 | 0.79 | EHMT1 (0.70) | DOT1LAMD1ADORA1DPP4MEN1 | |
| SCHEMBL15984531 | 0.79 | EHMT1 (0.70) | DOT1LAMD1ADORA1DPP4MEN1 | |
| SCHEMBL20097062 | 0.79 | EHMT1 (0.70) | DOT1LAMD1ADORA1DPP4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018075947-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF RNA VIRAL INFECTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-04-26 | — | — | WO | disclosed |