Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18236740 | 0.79 | IKZF1 (0.35) | IKZF1IKZF2 | |
| SCHEMBL18236727 | 0.79 | IKZF1 (0.35) | IKZF1IKZF2 | |
| SCHEMBL11461726 | 0.79 | IKZF1 (0.35) | IKZF1IKZF2 | |
| SCHEMBL20072972 | 0.77 | IKZF1 (0.34) | IKZF1IKZF2 | |
| SCHEMBL19773379 | 0.76 | IKZF1 (0.34) | IKZF1IKZF2 | |
| SCHEMBL18236736 | 0.75 | KAT2B (0.33) | IKZF1IKZF2 | |
| SCHEMBL20073129 | 0.74 | IKZF1 (0.33) | IKZF1IKZF2 | |
| SCHEMBL3457206 | 0.73 | IKZF1 (0.32) | IKZF1IKZF2 | |
| SCHEMBL24317839 | 0.73 | IKZF1 (0.33) | IKZF1IKZF2 | |
| SCHEMBL4537106 | 0.71 | FUCA1 (0.39) | IKZF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10646486-B2 | Polycyclic-carbamoylpyridone compounds and their pharmaceutical use | GILEAD SCIENCES, INC. (US) | 2020-05-12 | — | — | US | disclosed |
| US-20180110776-A1 | POLYCYCLICCARBAMOYLPYRIDONE COMPOUNDS AND THEIR PHARMACEUTICAL USE | GILEAD SCIENCES, INC. | 2018-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180110776-A1 | POLYCYCLICCARBAMOYLPYRIDONE COMPOUNDS AND THEIR PHARMACEUTICAL USE | PAICS, RPL5, CYP3A43 | IKZF1 1977/4885IKZF2 2881/4885 |
| US-10646486-B2 | Polycyclic-carbamoylpyridone compounds and their pharmaceutical use | CPS1, PAICS, C9 | IKZF1 1705/4885IKZF2 1871/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.