Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 17/20 | 0.66 |
| ▸ | WNT1 | P04628 | 10/20 | 0.66 |
| ▸ | CLK2 | P49760 | 4/20 | 0.57 |
| ▸ | CLK3 | P49761 | 4/20 | 0.57 |
| ▸ | GSK3B | P49841 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20097264 | 0.93 | DYRK1A (0.61) | DYRK1AWNT1CLK2CLK3GSK3B | |
| SCHEMBL14785592 | 0.89 | DYRK1A (0.83) | DYRK1AWNT1CLK2CLK3 | |
| SCHEMBL20097420 | 0.84 | DYRK1A (0.60) | DYRK1AWNT1CLK2CLK3 | |
| SCHEMBL23890021 | 0.84 | DYRK1A (0.61) | DYRK1AWNT1CLK2CLK3GSK3B | |
| SCHEMBL20097351 | 0.83 | DYRK1A (0.82) | DYRK1AWNT1CLK2CLK3 | |
| SCHEMBL20097349 | 0.82 | DYRK1A (0.81) | DYRK1AWNT1CLK2CLK3 | |
| SCHEMBL14792530 | 0.82 | DYRK1A (0.77) | DYRK1AWNT1CLK2CLK3GSK3B | |
| SCHEMBL20097299 | 0.81 | DYRK1A (0.62) | DYRK1AWNT1CLK2CLK3 | |
| SCHEMBL14792061 | 0.80 | DYRK1A (0.82) | DYRK1AWNT1CLK2CLK3GSK3B | |
| SCHEMBL14804107 | 0.80 | DYRK1A (0.83) | DYRK1AWNT1CLK2CLK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018075858-A1 | METHODS OF USING INDAZOLE-3-CARBOXAMIDES AND THEIR USE AS WNT/B-CATENIN SIGNALING PATHWAY INHIBITORS | SAMUMED, LLC (US) | 2018-04-26 | — | — | WO | disclosed |