Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 18/20 | 0.81 |
| ▸ | WNT1 | P04628 | 15/20 | 0.81 |
| ▸ | CLK2 | P49760 | 13/20 | 0.68 |
| ▸ | CLK3 | P49761 | 13/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20097436 | 0.99 | DYRK1A (0.80) | DYRK1AWNT1CLK2CLK3 | |
| SCHEMBL20097433 | 0.92 | DYRK1A (0.69) | DYRK1AWNT1CLK2CLK3 | |
| SCHEMBL20097345 | 0.91 | DYRK1A (0.68) | DYRK1AWNT1CLK2CLK3 | |
| SCHEMBL20097307 | 0.90 | DYRK1A (0.81) | DYRK1AWNT1CLK2CLK3 | |
| SCHEMBL31060154 | 0.90 | DYRK1A (1.00) | DYRK1AWNT1CLK2CLK3 | |
| SCHEMBL17095540 | 0.90 | DYRK1A (1.00) | DYRK1AWNT1CLK2CLK3 | |
| SCHEMBL14792370 | 0.90 | DYRK1A (1.00) | DYRK1AWNT1CLK2CLK3 | |
| SCHEMBL20097162 | 0.89 | DYRK1A (0.66) | DYRK1AWNT1CLK2CLK3 | |
| SCHEMBL20097408 | 0.89 | DYRK1A (0.67) | DYRK1AWNT1CLK2CLK3 | |
| SCHEMBL14792542 | 0.89 | DYRK1A (0.98) | DYRK1AWNT1CLK2CLK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018075858-A1 | METHODS OF USING INDAZOLE-3-CARBOXAMIDES AND THEIR USE AS WNT/B-CATENIN SIGNALING PATHWAY INHIBITORS | SAMUMED, LLC (US) | 2018-04-26 | — | — | WO | disclosed |