Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 4/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | THPO | P40225 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5665498 | 0.79 | APP (0.35) | GRM5APPNPSR1TSHRALDH1A1 | |
| SCHEMBL11357058 | 0.70 | GRM5 (0.37) | GRM5APPNPSR1TSHR | |
| SCHEMBL406538 | 0.65 | — | — | |
| SCHEMBL4111644 | 0.65 | — | — | |
| SCHEMBL16199674 | 0.65 | — | — | |
| SCHEMBL497768 | 0.65 | TSHR (0.48) | GRM5APPNPSR1TSHRNPC1 | |
| Diphenylacetylene SCHEMBL619305 | 0.65 | APP (0.60) | GRM5APPTSHRNPC1MTOR | |
| Diphenylacetylene SCHEMBL339222 | 0.65 | APP (0.60) | GRM5APPTSHRNPC1MTOR | |
| Phenylacetylene SCHEMBL27726827 | 0.63 | HDAC8 (0.44) | GRM5APPNPSR1TSHRALDH1A1 | |
| Trimethylammonium SCHEMBL27539624 | 0.63 | NPSR1 (0.45) | GRM5APPNPSR1TSHRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110151576-A1 | METHOD TO ASSESS MULTIPHASE FLUID COMPOSITIONS | LUX INNOVATE LIMITED (GB) | 2011-06-23 | — | — | US | claimed |