Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 17/20 | 0.67 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.67 |
| ▸ | PIK3R1 | P27986 | 5/20 | 0.67 |
| ▸ | MTOR | P42345 | 11/20 | 0.62 |
| ▸ | PIK3CG | P48736 | 7/20 | 0.62 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.62 |
| ▸ | PIK3C2B | O00750 | 2/20 | 0.62 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.62 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.62 |
| ▸ | PRKDC | P78527 | 2/20 | 0.62 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.62 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.62 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.62 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.62 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.62 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.62 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.62 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.62 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17078398 | 0.90 | HDAC1 (0.82) | PIK3CAHDAC1PIK3R1MTORPIK3CG | |
| SCHEMBL18505752 | 0.90 | PIK3CA (0.82) | PIK3CAHDAC1PIK3R1MTORPIK3CG | |
| SCHEMBL18505724 | 0.86 | HDAC1 (0.83) | PIK3CAHDAC1PIK3R1MTORPIK3CG | |
| SCHEMBL20097873 | 0.83 | PIK3CA (0.81) | PIK3CAHDAC1PIK3R1MTORPIK3CG | |
| SCHEMBL3128061 | 0.81 | PIK3CA (1.00) | PIK3CAHDAC1PIK3R1MTORPIK3CG | |
| SCHEMBL17087356 | 0.80 | HDAC1 (1.00) | PIK3CAHDAC1PIK3R1MTORPIK3CG | |
| SCHEMBL17078401 | 0.77 | HDAC1 (1.00) | PIK3CAHDAC1PIK3R1MTORPIK3CG | |
| SCHEMBL18505756 | 0.76 | HDAC1 (0.68) | PIK3CAHDAC1PIK3R1MTORPIK3CG | |
| SCHEMBL18505721 | 0.76 | HDAC1 (0.81) | PIK3CAHDAC1PIK3R1MTORPIK3CG | |
| SCHEMBL18505758 | 0.75 | HDAC1 (0.83) | PIK3CAHDAC1PIK3R1MTORPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9957270-B2 | Fused pyrimidine-based hydroxamate derivatives | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2018-05-01 | — | — | US | disclosed |