SCHEMBL2009960

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2002493	0.90	MAPK14 (0.41)	ERN1ALDH1A1HSD17B10S1PR5FFAR1
	SCHEMBL2013480	0.89	MRGPRX4 (0.40)	ERN1ALDH1A1S1PR5MAPK14MAPT
	SCHEMBL2004763	0.89	S1PR5 (0.39)	ERN1ALDH1A1S1PR5MAPK14MAPT
	SCHEMBL2006708	0.87	MRGPRX4 (0.40)	ERN1S1PR5MAPK14MAPTCDK1
	SCHEMBL2003916	0.85	S1PR5 (0.40)	ERN1ALDH1A1S1PR5FFAR1PPARD
	SCHEMBL2006324	0.84	MAPT (0.37)	ALDH1A1HSD17B10S1PR5MAPK14MAPT
	SCHEMBL12572463	0.84	S1PR5 (0.36)	ERN1ALDH1A1S1PR5MAPK14MAPT
	SCHEMBL2002561	0.82	MAPK14 (0.41)	ERN1ALDH1A1MAPK14CSF1RMAP4K1
	SCHEMBL2009185	0.81	CYP11B1 (0.39)	ALDH1A1HSD17B10MAPK1NPSR1LMNA
	SCHEMBL2005842	0.81	ERN1 (0.41)	ERN1S1PR5MAPK14MAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.