Abietic Acid

Abietic Acid

SCHEMBL2010001

CC(C)C1=CC2=CCC3[C@](C)(CCC[C@]3(C)C(=O)O)[C@H]2CC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 3/20 1.00
ALOX15 P16050 3/20 1.00
PDK1 Q15118 2/20 1.00
PDK2 Q15119 2/20 1.00
PDK3 Q15120 2/20 1.00
PDK4 Q16654 2/20 1.00
LMNA P02545 2/20 1.00
ALDH1A1 P00352 2/20 1.00
CYP2C9 P11712 2/20 1.00
CYP2C19 P33261 2/20 1.00
SLCO1B3 Q9NPD5 1/20 1.00
SLCO1B1 Q9Y6L6 1/20 1.00
GABRA1 P14867 1/20 1.00
GABRB2 P47870 1/20 1.00
CYP3A4 P08684 1/20 1.00
MAPT P10636 1/20 1.00
KDM4E B2RXH2 1/20 1.00
MAPK1 P28482 1/20 0.70
MEN1 O00255 1/20 0.63
KMT2A Q03164 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Abietic Acid SCHEMBL19798150 1.00 HSD17B10 (1.00) HSD17B10ALOX15PDK1PDK2PDK3
Abietic Acid SCHEMBL9892651 1.00 HSD17B10 (1.00) HSD17B10ALOX15PDK1PDK2PDK3
Abietic Acid SCHEMBL14700492 1.00 HSD17B10 (1.00) HSD17B10ALOX15PDK1PDK2PDK3
Abietic Acid SCHEMBL3917417 1.00 HSD17B10 (1.00) HSD17B10ALOX15PDK1PDK2PDK3
Abietic Acid SCHEMBL9927252 1.00 HSD17B10 (1.00) HSD17B10ALOX15PDK1PDK2PDK3
Abietic Acid SCHEMBL10038576 1.00 HSD17B10 (1.00) HSD17B10ALOX15PDK1PDK2PDK3
Abietic Acid SCHEMBL16268652 1.00 HSD17B10 (1.00) HSD17B10ALOX15PDK1PDK2PDK3
Abietic Acid SCHEMBL678976 1.00 HSD17B10 (1.00) HSD17B10ALOX15PDK1PDK2PDK3
Abietic Acid SCHEMBL14706813 1.00 HSD17B10 (1.00) HSD17B10ALOX15PDK1PDK2PDK3
Abietic Acid SCHEMBL28888 1.00 HSD17B10 (1.00) HSD17B10ALOX15PDK1PDK2PDK3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120241156-A1 SELECTIVE FLUID WITH ANCHORING AGENT FOR WATER CONTROL SCHLUMBERGER TECHNOLOGY CORPORATION 2012-09-27 US claimed
EP-3626807-B1 BIOREFINING OF CRUDE TALL OIL SUNPINE AB (SE) 2022-04-20 EP disclosed
EP-3460031-B1 BIOREFINING OF CRUDE TALL OIL SUNPINE AB (SE) 2021-04-28 EP disclosed
EP-2935545-B1 BIOREFINING OF CRUDE TALL OIL SUNPINE AB (SE) 2020-08-19 EP disclosed
EP-2935546-B1 BIOREFINING OF CRUDE TALL OIL SUNPINE AB (SE) 2020-08-19 EP disclosed
EP-3626807-A1 BIOREFINING OF CRUDE TALL OIL SunPine AB (SE) 2020-03-25 EP disclosed
US-10442955-B2 Resin, composition and use DSM IP ASSETS B.V. (NL) 2019-10-15 US disclosed
EP-3460031-A1 BIOREFINING OF CRUDE TALL OIL SunPine AB (SE) 2019-03-27 EP disclosed
US-20180142121-A1 RESIN, COMPOSITION AND USE COVESTRO (NETHERLANDS) B.V. (NL) 2018-05-24 US disclosed
US-9902870-B2 Resin, composition and use DSM IP ASSETS B.V. (NL) 2018-02-27 US disclosed
US-8680181-B2 Process to hydrophobize cement-free mortars AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) 2014-03-25 US disclosed
WO-2013167662-A1 RESIN, COMPOSITION AND USE DSM IP ASSETS B.V. (NL) 2013-11-14 WO disclosed
EP-2534111-A1 PROCESS TO HYDROPHOBIZE CEMENT-FREE MORTARS Akzo Nobel Chemicals International B.V. (NL) 2012-12-19 EP disclosed
US-20120309875-A1 PROCESS TO HYDROPHOBIZE CEMENT-FREE MORTARS AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) 2012-12-06 US disclosed
US-20120241156-A1 SELECTIVE FLUID WITH ANCHORING AGENT FOR WATER CONTROL SCHLUMBERGER TECHNOLOGY CORPORATION 2012-09-27 US disclosed
WO-2011098412-A1 PROCESS TO HYDROPHOBIZE CEMENT-FREE MORTARS AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) 2011-08-18 WO disclosed
US-7964063-B2 Methods and compositions for papermaking GEORGIA TECH RESEARCH CORPORATION (US) 2011-06-21 US disclosed
US-20080087396-A1 Making modified fillers for papermaking; applying a modified filler to a composition comprising fiber to form a mixture, processing the mixture whereby producing a paper GEORGIA TECH RESEARCH CORPORATION (US) 2008-04-17 US disclosed
US-20030022973-A1 Moisture cured polyurethane hot melt adhesives with reactive tackifiers NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION 2003-01-30 US disclosed
WO-2002083807-A1 MOISTURE CURED POLYURETHANE HOT MELT ADHESIVES WITH REACTIVE TACKIFIERS NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) 2002-10-24 WO disclosed