Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | STS | P08842 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SCN1A | P35498 | 1/20 | 0.42 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.42 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.42 |
| ▸ | PREP | P48147 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20100938 | 1.00 | SMN1; SMN2 (0.55) | SMN1; SMN2HTTNPC1RAB9ASTS | |
| SCHEMBL20100952 | 0.85 | SMN1; SMN2 (0.41) | SMN1; SMN2HTTNPC1RAB9ASTS | |
| SCHEMBL20100937 | 0.81 | SMN1; SMN2 (0.47) | SMN1; SMN2HTTNPC1RAB9ASTS | |
| SCHEMBL20100942 | 0.80 | CYP2D6 (0.50) | SMN1; SMN2HTTNPC1RAB9AMAPT | |
| SCHEMBL110657 | 0.79 | SMN1; SMN2 (0.68) | SMN1; SMN2HTTNPC1RAB9ASTS | |
| SCHEMBL27647410 | 0.77 | SMN1; SMN2 (0.66) | SMN1; SMN2HTTNPC1RAB9ASTS | |
| SCHEMBL27647433 | 0.77 | SMN1; SMN2 (0.66) | SMN1; SMN2HTTNPC1RAB9ASTS | |
| SCHEMBL27647562 | 0.77 | SMN1; SMN2 (0.66) | SMN1; SMN2HTTNPC1RAB9ASTS | |
| SCHEMBL27667920 | 0.77 | SMN1; SMN2 (0.66) | SMN1; SMN2HTTNPC1RAB9ASTS | |
| SCHEMBL27647587 | 0.77 | SMN1; SMN2 (0.66) | SMN1; SMN2HTTNPC1RAB9ASTS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180116993-A1 | MODULATORS OF FARNESOID X RECEPTOR AND METHODS FOR THE USE THEREOF | XIAMEN UNIVERSITY (CN) | 2018-05-03 | — | — | US | disclosed |
| US-20180116993-A1 | MODULATORS OF FARNESOID X RECEPTOR AND METHODS FOR THE USE THEREOF | XIAMEN UNIVERSITY (CN) | 2018-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180116993-A1 | MODULATORS OF FARNESOID X RECEPTOR AND METHODS FOR THE USE THEREOF | NR1H4, FABP1, NR1H2 | SMN1; SMN2 4843/4885HTT 4532/4885NPC1 126/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.