Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 10/20 | 0.41 |
| ▸ | LPAR2 | Q9HBW0 | 9/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.41 |
| ▸ | ACHE | P22303 | 6/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21219396 | 0.98 | LPAR3 (0.38) | LPAR3LPAR2LPAR1ACHEALDH1A1 | |
| SCHEMBL21219378 | 0.91 | CYP3A4 (0.34) | LPAR3LPAR2LPAR1 | |
| SCHEMBL4147128 | 0.84 | — | — | |
| SCHEMBL11315928 | 0.81 | LPAR3 (0.57) | LPAR3LPAR2LPAR1MEN1THRB | |
| SCHEMBL10826446 | 0.81 | LPAR3 (0.57) | LPAR3LPAR2LPAR1MEN1THRB | |
| SCHEMBL21569461 | 0.81 | LPAR3 (0.57) | LPAR3LPAR2LPAR1MEN1THRB | |
| SCHEMBL21569439 | 0.81 | LPAR3 (0.57) | LPAR3LPAR2LPAR1MEN1THRB | |
| SCHEMBL212017 | 0.81 | CYP3A4 (0.43) | LPAR3LPAR2LPAR1ACHEALDH1A1 | |
| SCHEMBL21569457 | 0.81 | LPAR3 (0.57) | LPAR3LPAR2LPAR1MEN1THRB | |
| SCHEMBL21569448 | 0.81 | LPAR3 (0.57) | LPAR3LPAR2LPAR1MEN1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052107-B1 | ORGANIC COMPOUNDS TO TREAT HEPATITIS B VIRUS | NOVARTIS AG (CH) | 2018-05-02 | — | — | EP | disclosed |