SCHEMBL20103494

SCHEMBL20103494

COc1ccc(F)c(C2CCC(COc3cccc(C(C4CC4)C(C)(F)C(=O)O)c3)CC2)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21644833 1.00 FFAR1 (1.00) FFAR1
SCHEMBL21688316 1.00 FFAR1 (1.00) FFAR1
SCHEMBL20103292 1.00 FFAR1 (1.00) FFAR1
SCHEMBL20103214 1.00 FFAR1 (1.00) FFAR1
SCHEMBL21644826 1.00 FFAR1 (1.00) FFAR1
SCHEMBL21644883 1.00 FFAR1 (1.00) FFAR1
SCHEMBL21688318 1.00 FFAR1 (1.00) FFAR1
SCHEMBL20103671 0.93 FFAR1 (0.87) FFAR1
SCHEMBL21688317 0.93 FFAR1 (0.87) FFAR1
SCHEMBL21688294 0.92 FFAR1 (0.86) FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018081047-A1 CYCLOHEXYL GPR40 AGONISTS FOR THE TREATMENT OF TYPE II DIABETES JANSSEN PHARMACEUTICA NV (BE) 2018-05-03 WO disclosed