Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 16/20 | 0.61 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20103237 | 0.92 | FFAR1 (0.66) | FFAR1PPARD | |
| SCHEMBL20103624 | 0.91 | FFAR1 (0.60) | FFAR1SLC2A1PPARD | |
| SCHEMBL20103349 | 0.83 | FFAR1 (0.55) | FFAR1 | |
| SCHEMBL20103338 | 0.83 | FFAR1 (0.68) | FFAR1 | |
| SCHEMBL20103491 | 0.80 | FFAR1 (0.87) | FFAR1 | |
| SCHEMBL21644856 | 0.80 | FFAR1 (0.87) | FFAR1 | |
| SCHEMBL21688390 | 0.80 | FFAR1 (0.87) | FFAR1 | |
| SCHEMBL21644853 | 0.80 | FFAR1 (0.87) | FFAR1 | |
| SCHEMBL20103549 | 0.79 | FFAR1 (0.52) | FFAR1 | |
| SCHEMBL20103295 | 0.78 | FFAR1 (0.48) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018081047-A1 | CYCLOHEXYL GPR40 AGONISTS FOR THE TREATMENT OF TYPE II DIABETES | JANSSEN PHARMACEUTICA NV (BE) | 2018-05-03 | — | — | WO | disclosed |