⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2010427 | 1.00 | — | — | |
| Formic Acid SCHEMBL27721652 | 0.92 | GRIA2 (0.41) | — | |
| SCHEMBL16824586 | 0.87 | GRIA2 (0.40) | — | |
| Trifluoroacetic Acid SCHEMBL6642142 | 0.78 | KDM1A (0.35) | — | |
| SCHEMBL4707813 | 0.75 | MAPKAPK2 (0.42) | — | |
| SCHEMBL6643857 | 0.75 | MAPKAPK2 (0.42) | — | |
| SCHEMBL668162 | 0.74 | — | — | |
| SCHEMBL1162649 | 0.74 | — | — | |
| SCHEMBL1162329 | 0.74 | — | — | |
| SCHEMBL27585894 | 0.74 | GRIA2 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113795249-B | Pharmaceutical compounds for treating complement-mediated disorders | 艾其林医药公司 | 2025-02-25 | — | — | CN | disclosed |
| CN-113795249-A | Pharmaceutical compounds for the treatment of complement-mediated disorders | 艾其林医药公司 | 2021-12-14 | — | — | CN | disclosed |
| CN-108383902-A | Insulin analog dimer | 印第安纳大学研究及科技有限公司 | 2018-08-10 | — | — | CN | disclosed |
| CN-104981251-B | Insulin analog dimers | 印第安纳大学研究及科技有限公司 | 2018-03-20 | — | — | CN | disclosed |
| CN-104788361-B | The synthetic method of the formic acid derivates of 5 azaspiros [2.4] heptane 6 | 杭州科巢生物科技有限公司 | 2017-06-30 | — | — | CN | disclosed |
| CN-103068842-B | Insulin receptor INSR is had highly active single-chain insulin agonist | 印第安纳大学研究及科技有限公司 | 2016-10-19 | — | — | CN | disclosed |
| CN-105377251-A | Mobilizing agents and uses thereof | MATER MEDICAL RES INST LTD | 2016-03-02 | — | — | CN | disclosed |
| CN-104981251-A | Insulin analog dimers | UNIV INDIANA RES & TECH CORP | 2015-10-14 | — | — | CN | disclosed |
| CN-104788361-A | Synthetic method for 5-azaspiro[2.4]heptane-6-formic acid derivative | HANGZHOU CHEMINSPIRE TECHNOLOGIES CO LTD | 2015-07-22 | — | — | CN | disclosed |
| EP-2366704-B1 | Inhibitors of serine proteases | VERTEX PHARMA (US) | 2013-10-23 | — | — | EP | disclosed |
| EP-2114958-A1 | INHIBITORS OF SERINE PROTEASES FOR THE TREATMENT OF HCV INFECTIONS | Vertex Pharmceuticals Incorporated (US) | 2009-11-11 | — | — | EP | disclosed |
| CN-101316852-A | Inhibitors of serine proteases | VERTEX PHARMA (US) | 2008-12-03 | — | — | CN | disclosed |
| WO-2008106139-A1 | INHIBITORS OF SERINE PROTEASES FOR THE TREATMENT OF HCV INFECTIONS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2008-09-04 | — | — | WO | disclosed |
| EP-1917269-A2 | INHIBITORS OF SERINE PROTEASES | Vertex Pharmaceuticals Incorporated (US) | 2008-05-07 | — | — | EP | disclosed |
| US-20070179167-A1 | Inhibitors of serine proteases | VERTEX PHARMACEUTICALS INCORPORATED | 2007-08-02 | — | — | US | disclosed |
| WO-2007025307-A2 | INHIBITORS OF SERINE PROTEASES | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2007-03-01 | — | — | WO | disclosed |
| EP-0828851-B1 | TRIPEPTIDYLPEPTIDASE INHIBITORS | INST NAT SANTE ETDE LA RECH ME (FR) | 2005-07-20 | — | — | EP | disclosed |
| US-6403561-B1 | DISORDERS ASSOCIATED WITH THE INACTIVATION OR EXCESSIVE DEGRADATION OF CHOLECYSTOKININ; INHIBITING THE ENZYMATIC HYDROLYSIS OF CHOLECYSTOKININ 1-(2(S)-AMINOBUTYRYL)-2(S)-INDOLINECARBOXYLIC ACID | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2002-06-11 | — | — | US | disclosed |
| EP-0828851-A2 | TRIPEPTIDYLPEPTIDASE INHIBITORS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1998-03-18 | — | — | EP | disclosed |
| WO-1996035805-A2 | TRIPEPTIDYLPEPTIDASE INHIBITORS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1996-11-14 | — | — | WO | disclosed |