SCHEMBL20104789

SCHEMBL20104789

NC(CCCNC(N)C1(N)CCCCCCC1)C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OTC P00480 1/20 0.40
GSR P00390 2/20 0.40
ARG2 P78540 4/20 0.37
ARG1 P05089 3/20 0.37
CYP1A2 P05177 2/20 0.36
CYP2C19 P33261 2/20 0.36
NOS2 P35228 2/20 0.36
GLA P06280 1/20 0.36
TSHR P16473 1/20 0.36
NFKB1 P19838 1/20 0.36
APEX1 P27695 1/20 0.36
DDAH1 O94760 3/20 0.36
NOD1 Q9Y239 1/20 0.35
GRM8 O00222 1/20 0.34
GRM6 O15303 1/20 0.34
GRIN2D O15399 1/20 0.34
GRIN3B O60391 1/20 0.34
GRIK1 P39086 1/20 0.34
GRM5 P41594 1/20 0.34
GRIA1 P42261 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20104707 0.76
SCHEMBL15209382 0.74 OTC (0.51) OTCGSRARG2ARG1CYP1A2
SCHEMBL2235195 0.74 OTC (0.51) OTCGSRARG2ARG1CYP1A2
SCHEMBL14844417 0.73 GSR (0.50) OTCGSRARG2ARG1CYP1A2
SCHEMBL18741586 0.73 GSR (0.50) OTCGSRARG2ARG1CYP1A2
SCHEMBL8709636 0.73 GSR (0.50) OTCGSRARG2ARG1CYP1A2
SCHEMBL13337953 0.73 GSR (0.54) OTCGSRARG2ARG1CYP1A2
SCHEMBL17274213 0.73 GSR (0.54) OTCGSRARG2ARG1CYP1A2
SCHEMBL20104775 0.71 GSR (0.48) GSRARG2ARG1CYP1A2CYP2C19
SCHEMBL20104774 0.71 GSR (0.48) GSRARG2ARG1CYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11195597-B2 Method and device for calculating acid dissociation constant, and program FUJITSU LIMITED (JP) 2021-12-07 US disclosed
US-20180121632-A1 METHOD AND DEVICE FOR CALCULATING ACID DISSOCIATION CONSTANT, AND PROGRAM FUJITSU LIMITED (JP) 2018-05-03 US disclosed