Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 20/20 | 0.61 |
| ▸ | JAK2 | O60674 | 19/20 | 0.61 |
| ▸ | JAK1 | P23458 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20106508 | 1.00 | NTRK1 (0.61) | NTRK1JAK2JAK1 | |
| SCHEMBL30013959 | 1.00 | NTRK1 (0.61) | NTRK1JAK2JAK1 | |
| SCHEMBL2599290 | 0.92 | NTRK1 (0.68) | NTRK1JAK2JAK1 | |
| SCHEMBL2599293 | 0.92 | NTRK1 (0.68) | NTRK1JAK2JAK1 | |
| SCHEMBL20602710 | 0.91 | NTRK1 (0.66) | NTRK1JAK2JAK1 | |
| SCHEMBL21219502 | 0.91 | NTRK1 (0.66) | NTRK1JAK2JAK1 | |
| SCHEMBL18783276 | 0.89 | NTRK1 (0.77) | NTRK1JAK2JAK1 | |
| SCHEMBL17820741 | 0.89 | NTRK1 (0.77) | NTRK1JAK2JAK1 | |
| SCHEMBL30013797 | 0.89 | NTRK1 (0.77) | NTRK1JAK2JAK1 | |
| SCHEMBL20624671 | 0.87 | NTRK1 (0.58) | NTRK1JAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019005796-A1 | PROCESS FOR THE PREPARATION OF PYRAZOLO[1,5-a]PYRIMIDINES AND SALTS THEREOF | ZHAO QIAN (US) | 2019-01-03 | — | — | WO | disclosed |
| WO-2018081417-A2 | PROCESS FOR THE PREPARATION OF PYRAZOLO[1,5-a]PYRIMIDINES AND SALTS THEREOF | ZHAO QIAN (US) | 2018-05-03 | — | — | WO | disclosed |